HBV Target gene Detail Information

> RPL34 Gene Search Result


Gene Information
Gene Name RPL34
Gene ID 6164
Gene Full Name ribosomal protein L34
Gene Alias L34
Transcripts ENSG00000109475
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;Endoplasmic reticulum;Nucleoli;
HPA Protein Class Info Predicted intracellular proteins, Ribosomal proteins
Uniport_ID P49207
HGNC ID HGNC:10340
VEGA ID OTTHUMG00000131839
OMIM ID 616862
String ID 9606.ENSP00000378163
PharmGKB ID PA34723
Target gene [RPL34] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1016603 chr4 1 1 View
1016604 chr4 1 1 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of RPL34 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
RPL34 expression: Low -> High
Lollipop of RPL34 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of RPL34 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of RPL34 expression and immune infiltrating cell level correlation result in HBV+ samples
RPL34 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).