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HBV Target gene Detail Information

> RPH3AL Gene Search Result


Gene Information
Gene Name RPH3AL
Gene ID 9501
Gene Full Name rabphilin 3A like (without C2 domains)
Gene Alias NOC2
Transcripts ENSG00000282013
Virus HBV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q9UNE2
HGNC ID HGNC:10296
VEGA ID OTTHUMG00000190900
OMIM ID 604881
String ID 9606.ENSP00000328977
PharmGKB ID PA34658
Target gene [RPH3AL] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1005996 chr17 45 45 View
1404498 chr17 41 30 18 89 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of RPH3AL expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
RPH3AL expression: Low -> High
Lollipop of RPH3AL expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of RPH3AL expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of RPH3AL expression and immune infiltrating cell level correlation result in HBV+ samples
RPH3AL expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).