HBV Target gene Detail Information

> RPE65 Gene Search Result

Gene Information

Gene Name	RPE65
Gene ID	6121
Gene Full Name	RPE65, retinoid isomerohydrolase
Gene Alias	p63; BCO3; LCA2; RP20; rd12; mRPE65; sRPE65
Transcripts	ENSG00000116745
Virus	HBV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins
Uniport_ID	Q16518
HGNC ID	HGNC:10294
VEGA ID	OTTHUMG00000009208
OMIM ID	180069
String ID	9606.ENSP00000262340
Drugbank ID	BE0009161; BE0009149
PharmGKB ID	PA34655

Target gene [RPE65] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1004528	chr1	53	7	18	78	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of RPE65 expression and immune infiltrating cell level correlation result in HBV+ samples
RPE65 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).