HIV Target gene Detail Information

> RPAP3 Gene Search Result

Gene Information

Gene Name	RPAP3
Gene ID	79657
Gene Full Name	RNA polymerase II associated protein 3
Gene Alias	Tah1; hSpagh
Transcripts	ENSG00000005175
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q9H6T3
HGNC ID	HGNC:26151
VEGA ID	OTTHUMG00000169668
OMIM ID	611477
String ID	9606.ENSP00000005386
PharmGKB ID	PA162401982

Target gene [RPAP3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003920	chr12	49	1	2	52	View
4007038	chr12	21			21	View
4012574	chr12	3	2		5	View
4014848	chr12	1	1		2	View
4015600	chr12	1			1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of RPAP3 expression and immune infiltrating cell level correlation result in HIV+ samples
RPAP3 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of RPAP3 expression and immune infiltrating cell level correlation result in HIV+ samples
RPAP3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).