HIV Target gene Detail Information

> RPA3 Gene Search Result

Gene Information

Gene Name	RPA3
Gene ID	6119
Gene Full Name	replication protein A3
Gene Alias	REPA3; RP-A p14
Transcripts	ENSG00000106399
Virus	HIV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	P35244
HGNC ID	HGNC:10291
VEGA ID	OTTHUMG00000023748
OMIM ID	179837
String ID	9606.ENSP00000223129
PharmGKB ID	PA34653

Target gene [RPA3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4004776	chr7	32	6	1	39	View
4010135	chr7	7	3		10	View
4012130	chr7	4	1		5	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of RPA3 expression and immune infiltrating cell level correlation result in HIV+ samples
RPA3 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of RPA3 expression and immune infiltrating cell level correlation result in HIV+ samples
RPA3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).