Gene Information
Gene Name
|
ROS1 |
Gene ID
|
6098
|
Gene Full Name
|
ROS proto-oncogene 1, receptor tyrosine kinase |
Gene Alias
|
ROS; MCF3; c-ros-1 |
Transcripts
|
ENSG00000047936
|
Virus
|
HBV |
Gene Type
|
protein coding |
HPA Location Info
|
Vesicles;
|
Membrane Info
|
Predicted membrane proteins |
HPA Protein Class Info
|
Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins |
Gene Function
|
Oncogene
|
Uniport_ID
|
P08922
|
HGNC ID
|
HGNC:10261
|
VEGA ID
|
OTTHUMG00000016188
|
OMIM ID
|
165020 |
String ID
|
9606.ENSP00000357494
|
Drugbank ID
|
BE0009488;
BE0009534
|
PharmGKB ID
|
PA34633
|
FDA Approved Drug
|
Entrectinib;Crizotinib;Lorlatinib |
Target gene [ROS1] related to VISs
DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
1009816 |
chr3 |
14 |
|
|
14 |
View |
1013240 |
chr6 |
3 |
2 |
|
5 |
View |
1013241 |
chr6 |
3 |
2 |
|
5 |
View |
Relationship between gene expression and immune infiltrating cell level
Data ID |
Disease |
Sample number |
Sample type |
LIHC (TCGA) |
Liver hepatocellular carcinoma |
424 |
Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18) |
> Dataset: LIHC
|
HeatMap of cell type fractions in all samples
|
Lollipop of ROS1 expression and immune infiltrating cell level correlation result in HBV+ samples
|
ROS1 expression: Low -> High
|
|
|
|
|