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HBV Target gene Detail Information

> RORC Gene Search Result


Gene Information
Gene Name RORC
Gene ID 6097
Gene Full Name RAR related orphan receptor C
Gene Alias TOR; RORG; RZRG; IMD42; NR1F3; RZR-GAMMA
Transcripts ENSG00000143365
Virus HBV
Gene Type protein coding
HPA Location Info Nuclear bodies;
HPA Protein Class Info Disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors
Uniport_ID P51449
HGNC ID HGNC:10260
VEGA ID OTTHUMG00000013053
OMIM ID 602943
String ID 9606.ENSP00000327025
PharmGKB ID PA34632
Target gene [RORC] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1004338 chr1 33 30 22 85 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of RORC expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
RORC expression: Low -> High
Lollipop of RORC expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of RORC expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of RORC expression and immune infiltrating cell level correlation result in HBV+ samples
RORC expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).