HIV Target gene Detail Information

> RORA Gene Search Result

Gene Information

Gene Name	RORA
Gene ID	6095
Gene Full Name	RAR related orphan receptor A
Gene Alias	ROR1; ROR2; ROR3; RZRA; NR1F1; IDDECA; RZR-ALPHA
Transcripts	ENSG00000069667
Virus	HIV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors
Uniport_ID	P35398
HGNC ID	HGNC:10258
VEGA ID	OTTHUMG00000132769
OMIM ID	600825
String ID	9606.ENSP00000261523
Drugbank ID	BE0004545
PharmGKB ID	PA34630

Target gene [RORA] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002424	chr15	67	8	20	95	View
4004704	chr15	11	25	4	40	View
4005484	chr15	8	21	3	32	View
4010400	chr15	3		6	9	View
4011364	chr15	3	4		7	View
4014378	chr15	1	1		2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of RORA expression and immune infiltrating cell level correlation result in HIV+ samples
RORA expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of RORA expression and immune infiltrating cell level correlation result in HIV+ samples
RORA expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).