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HTLV1 Target gene Detail Information

> ROPN1 Gene Search Result


Gene Information
Gene Name ROPN1
Gene ID 54763
Gene Full Name rhophilin associated tail protein 1
Gene Alias CT91; ODF6; ROPN1A; RHPNAP1; ropporin
Transcripts ENSG00000065371
Virus HTLV1
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q9HAT0
HGNC ID HGNC:17692
VEGA ID OTTHUMG00000159556
OMIM ID 611757
String ID 9606.ENSP00000184183
PharmGKB ID PA134952827
Target gene [ROPN1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6013815 chr3 18 18 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of ROPN1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ROPN1 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of ROPN1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ROPN1 expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of ROPN1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ROPN1 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).