HBV Target gene Detail Information

> ROBO2 Gene Search Result

Gene Information

Gene Name	ROBO2
Gene ID	6092
Gene Full Name	roundabout guidance receptor 2
Gene Alias	SAX3
Transcripts	ENSG00000185008
Virus	HBV
Gene Type	protein coding
HPA Location Info	Centriolar satellite;Nucleoplasm;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q9HCK4
HGNC ID	HGNC:10250
VEGA ID	OTTHUMG00000158935
OMIM ID	602431
String ID	9606.ENSP00000417335
PharmGKB ID	PA34621

Target gene [ROBO2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1004647	chr3	64	9		73	View
1007039	chr3	18	9	4	31	View
1007040	chr3	19	8	4	31	View
1012718	chr3	5	1		6	View
1013963	chr3	2	1	1	4	View
1014729	chr3	1	1	1	3	View
1017627	chr3				0	View
1401173	chr3				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of ROBO2 expression and immune infiltrating cell level correlation result in HBV+ samples
ROBO2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).