HIV Target gene Detail Information

> RNF43 Gene Search Result

Gene Information

Gene Name	RNF43
Gene ID	54894
Gene Full Name	ring finger protein 43
Gene Alias	URCC; SSPCS; RNF124
Transcripts	ENSG00000108375
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins
Gene Function	Oncogene
Uniport_ID	Q68DV7
HGNC ID	HGNC:18505
VEGA ID	OTTHUMG00000179077
OMIM ID	612482
String ID	9606.ENSP00000463069
PharmGKB ID	PA34441

Target gene [RNF43] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4008460	chr17	2	9	4	15	View
4014162	chr17	1	1		2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of RNF43 expression and immune infiltrating cell level correlation result in HIV+ samples
RNF43 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).