HTLV1 Target gene Detail Information

> RNF32 Gene Search Result


Gene Information
Gene Name RNF32
Gene ID 140545
Gene Full Name ring finger protein 32
Gene Alias HSD15; LMBR2; FKSG33
Transcripts ENSG00000105982
Virus HTLV1
Gene Type protein coding
HPA Location Info Cytosol;Nuclear bodies;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q9H0A6
HGNC ID HGNC:17118
VEGA ID OTTHUMG00000151440
OMIM ID 610241
String ID 9606.ENSP00000385285
PharmGKB ID PA34435
Target gene [RNF32] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6023332 chr7 2 2 4 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of RNF32 expression and immune infiltrating cell level correlation result in HTLV1+ samples
RNF32 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of RNF32 expression and immune infiltrating cell level correlation result in HTLV1+ samples
RNF32 expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of RNF32 expression and immune infiltrating cell level correlation result in HTLV1+ samples
RNF32 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).