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HBV Target gene Detail Information

> RNF25 Gene Search Result


Gene Information
Gene Name RNF25
Gene ID 64320
Gene Full Name ring finger protein 25
Gene Alias AO7
Transcripts ENSG00000163481
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;Actin filaments;Nucleoplasm;
HPA Protein Class Info Enzymes, Predicted intracellular proteins
Uniport_ID Q96BH1
HGNC ID HGNC:14662
VEGA ID OTTHUMG00000133077
OMIM ID 616014
String ID 9606.ENSP00000295704
PharmGKB ID PA34429
Target gene [RNF25] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1004696 chr2 69 3 72 View
1007267 chr2 27 1 28 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of RNF25 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
RNF25 expression: Low -> High
Lollipop of RNF25 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of RNF25 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of RNF25 expression and immune infiltrating cell level correlation result in HBV+ samples
RNF25 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).