HIV Target gene Detail Information

> RNF213 Gene Search Result

Gene Information

Gene Name	RNF213
Gene ID	57674
Gene Full Name	ring finger protein 213
Gene Alias	ALO17; MYMY2; MYSTR; NET57; C17orf27; KIAA1618
Transcripts	ENSG00000173821
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q63HN8
HGNC ID	HGNC:14539
VEGA ID	OTTHUMG00000161415
OMIM ID	613768
String ID	9606.ENSP00000464087
PharmGKB ID	PA162401681

Target gene [RNF213] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003514	chr17	2	35	23	60	View
4004743	chr17	39		1	40	View
4005666	chr17	27	3		30	View
4007512	chr17	2	16	1	19	View
4007615	chr17	6	8	4	18	View
4010373	chr17	9			9	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of RNF213 expression and immune infiltrating cell level correlation result in HIV+ samples
RNF213 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of RNF213 expression and immune infiltrating cell level correlation result in HIV+ samples
RNF213 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).