HTLV1 Target gene Detail Information

> RNF212 Gene Search Result

Gene Information

Gene Name	RNF212
Gene ID	285498
Gene Full Name	ring finger protein 212
Gene Alias	ZHP3
Transcripts	ENSG00000178222
Virus	HTLV1
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q495C1
HGNC ID	HGNC:27729
VEGA ID	OTTHUMG00000118997
OMIM ID	612041
String ID	9606.ENSP00000389709
PharmGKB ID	PA162401656

Target gene [RNF212] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6006656	chr4	57	4	4	65	View
6011744	chr4	16	8	1	25	View
6011795	chr4	16	8	1	25	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of RNF212 expression and immune infiltrating cell level correlation result in HTLV1+ samples
RNF212 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of RNF212 expression and immune infiltrating cell level correlation result in HTLV1+ samples
RNF212 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).