HIV Target gene Detail Information

> RNF19A Gene Search Result

Gene Information

Gene Name	RNF19A
Gene ID	25897
Gene Full Name	ring finger protein 19A, RBR E3 ubiquitin protein ligase
Gene Alias	RNF19
Transcripts	ENSG00000034677
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Enzymes, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q9NV58
HGNC ID	HGNC:13432
VEGA ID	OTTHUMG00000164707
OMIM ID	607119
String ID	9606.ENSP00000428968
PharmGKB ID	PA162401601

Target gene [RNF19A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003053	chr8	12	36	23	71	View
4004902	chr8	19	15	4	38	View
4005464	chr8	29	3		32	View
4006271	chr8	26			26	View
4006285	chr8	13	13		26	View
4007698	chr8	13	4	1	18	View
4010450	chr8	5	2	2	9	View
4015150	chr8		1		1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of RNF19A expression and immune infiltrating cell level correlation result in HIV+ samples
RNF19A expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of RNF19A expression and immune infiltrating cell level correlation result in HIV+ samples
RNF19A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).