HIV Target gene Detail Information

> RNF169 Gene Search Result

Gene Information

Gene Name	RNF169
Gene ID	254225
Gene Full Name	ring finger protein 169
Transcripts	ENSG00000166439
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nuclear bodies;Nucleoplasm;Cytosol;Nucleoli;Nucleoli rim;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	Q8NCN4
HGNC ID	HGNC:26961
VEGA ID	OTTHUMG00000165516
OMIM ID	618650
String ID	9606.ENSP00000299563
PharmGKB ID	PA142671054

Target gene [RNF169] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4004462	chr11	43	1		44	View
4007963	chr11	15	2		17	View
4008918	chr11	6	7		13	View
4016484	chr11				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of RNF169 expression and immune infiltrating cell level correlation result in HIV+ samples
RNF169 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of RNF169 expression and immune infiltrating cell level correlation result in HIV+ samples
RNF169 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).