HIV Target gene Detail Information

> RNF166 Gene Search Result

Gene Information

Gene Name	RNF166
Gene ID	115992
Gene Full Name	ring finger protein 166
Transcripts	ENSG00000158717
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Cytosol;Plasma membrane;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q96A37
HGNC ID	HGNC:28856
VEGA ID	OTTHUMG00000137863
OMIM ID	617178
String ID	9606.ENSP00000326095
PharmGKB ID	PA134915234

Target gene [RNF166] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003475	chr16	40	16	4	60	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of RNF166 expression and immune infiltrating cell level correlation result in HIV+ samples
RNF166 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of RNF166 expression and immune infiltrating cell level correlation result in HIV+ samples
RNF166 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).