HIV Target gene Detail Information

> RNF149 Gene Search Result

Gene Information

Gene Name	RNF149
Gene ID	284996
Gene Full Name	ring finger protein 149
Gene Alias	DNAPTP2
Transcripts	ENSG00000163162
Virus	HIV
Gene Type	protein coding
HPA Location Info	Plasma membrane;Vesicles;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Enzymes, Predicted membrane proteins
Uniport_ID	Q8NC42
HGNC ID	HGNC:23137
VEGA ID	OTTHUMG00000130685
String ID	9606.ENSP00000295317
PharmGKB ID	PA134895641

Target gene [RNF149] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4015653	chr2	1			1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of RNF149 expression and immune infiltrating cell level correlation result in HIV+ samples
RNF149 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of RNF149 expression and immune infiltrating cell level correlation result in HIV+ samples
RNF149 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).