HIV Target gene Detail Information

> RNF145 Gene Search Result

Gene Information

Gene Name	RNF145
Gene ID	153830
Gene Full Name	ring finger protein 145
Transcripts	ENSG00000145860
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;Plasma membrane;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Enzymes, Predicted membrane proteins
Uniport_ID	Q96MT1
HGNC ID	HGNC:20853
VEGA ID	OTTHUMG00000130306
String ID	9606.ENSP00000430955
PharmGKB ID	PA134876286

Target gene [RNF145] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4004953	chr5	37			37	View
4005576	chr5	31			31	View
4014634	chr5		2		2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of RNF145 expression and immune infiltrating cell level correlation result in HIV+ samples
RNF145 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of RNF145 expression and immune infiltrating cell level correlation result in HIV+ samples
RNF145 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).