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HPV Target gene Detail Information

> RNF128 Gene Search Result


Gene Information
Gene Name RNF128
Gene ID 79589
Gene Full Name ring finger protein 128, E3 ubiquitin protein ligase
Gene Alias GRAIL
Transcripts ENSG00000133135
Virus HPV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Enzymes, Predicted membrane proteins
Uniport_ID Q8TEB7
HGNC ID HGNC:21153
VEGA ID OTTHUMG00000022151
OMIM ID 300439
String ID 9606.ENSP00000255499
PharmGKB ID PA134868457
Target gene [RNF128] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5201697 chrX 20 20 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE140662 (GEO) Condyloma Acuminatum 8 Condyloma acuminata (HPV+)(5), Skin(3)
GSE65858 (GEO) Head and neck squamous cell carcinoma 270 Head and neck squamous cell carcinoma (EBV+)(73), Head and neck squamous cell carcinoma (EBV-)(197)
GSE55546 (GEO) Oropharyngeal squamous cell carcinoma 16 Oropharyngeal cancers (HPV+)(12), Normal (4)
GSE55544 (GEO) Oropharyngeal squamous cell carcinoma 23 Oropharyngeal cancers HPV Active (11), Oropharyngeal cancers HPV Inactive (4), Oropharyngeal cancers HPV Negative (8)
GSE55542 (GEO) Oropharyngeal squamous cell carcinoma 36 Oropharyngeal cancers HPV Active (12), Oropharyngeal cancers HPV Inactive (8), Oropharyngeal cancers HPV Negative (16)
GSE138080 (GEO) Cervical intraepithelial neoplasia 25 Normal (10), Cervical intraepithelial neoplasia (HPV+)(15)
GSE51993 (GEO) Cervical intraepithelial neoplasia 24 Cervical intraepithelial neoplasia (HPV+)(17), Normal(7)
HNSC (TCGA) Head and Neck squamous cell carcinoma 566 Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE140662

HeatMap of cell type fractions in all samples Lollipop of RNF128 expression and immune infiltrating cell level correlation result in HPV+ samples
RNF128 expression: Low -> High

> Dataset: GSE65858

HeatMap of cell type fractions in all samples Lollipop of RNF128 expression and immune infiltrating cell level correlation result in HPV+ samples
RNF128 expression: Low -> High

> Dataset: GSE55546

HeatMap of cell type fractions in all samples Lollipop of RNF128 expression and immune infiltrating cell level correlation result in HPV+ samples
RNF128 expression: Low -> High

> Dataset: GSE55544

HeatMap of cell type fractions in all samples Lollipop of RNF128 expression and immune infiltrating cell level correlation result in HPV+ samples
RNF128 expression: Low -> High

> Dataset: GSE55542

HeatMap of cell type fractions in all samples Lollipop of RNF128 expression and immune infiltrating cell level correlation result in HPV+ samples
RNF128 expression: Low -> High

> Dataset: GSE138080

HeatMap of cell type fractions in all samples Lollipop of RNF128 expression and immune infiltrating cell level correlation result in HPV+ samples
RNF128 expression: Low -> High

> Dataset: GSE51993

HeatMap of cell type fractions in all samples Lollipop of RNF128 expression and immune infiltrating cell level correlation result in HPV+ samples
RNF128 expression: Low -> High

> Dataset: HNSC

HeatMap of cell type fractions in all samples Lollipop of RNF128 expression and immune infiltrating cell level correlation result in HPV+ samples
RNF128 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).