HIV Target gene Detail Information

> RNF103 Gene Search Result

Gene Information

Gene Name	RNF103
Gene ID	7844
Gene Full Name	ring finger protein 103
Gene Alias	KF1; KF-1; HKF-1; ZFP103; ZFP-103
Transcripts	ENSG00000239305
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Enzymes, Predicted membrane proteins
Uniport_ID	O00237
HGNC ID	HGNC:12859
VEGA ID	OTTHUMG00000153197
OMIM ID	602507
String ID	9606.ENSP00000237455
PharmGKB ID	PA37448

Target gene [RNF103] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003440	chr2	50	11		61	View
4003542	chr2	10	49		59	View
4006691	chr2	9	14		23	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of RNF103 expression and immune infiltrating cell level correlation result in HIV+ samples
RNF103 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of RNF103 expression and immune infiltrating cell level correlation result in HIV+ samples
RNF103 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).