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HTLV1 Target gene Detail Information

> RLN2 Gene Search Result


Gene Information
Gene Name RLN2
Gene ID 6019
Gene Full Name relaxin 2
Gene Alias H2; RLXH2; H2-RLX; bA12D24.1.1; bA12D24.1.2
Transcripts ENSG00000107014
Virus HTLV1
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Predicted intracellular proteins, Predicted secreted proteins
Uniport_ID P04090
HGNC ID HGNC:10027
VEGA ID OTTHUMG00000019496
OMIM ID 179740
String ID 9606.ENSP00000371040
PharmGKB ID PA34400
Target gene [RLN2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6010202 chr9 32 32 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of RLN2 expression and immune infiltrating cell level correlation result in HTLV1+ samples
RLN2 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of RLN2 expression and immune infiltrating cell level correlation result in HTLV1+ samples
RLN2 expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of RLN2 expression and immune infiltrating cell level correlation result in HTLV1+ samples
RLN2 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).