HIV Target gene Detail Information

> RLF Gene Search Result

Gene Information

Gene Name	RLF
Gene ID	6018
Gene Full Name	rearranged L-myc fusion
Gene Alias	ZN-15L; ZNF292L
Transcripts	ENSG00000117000
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Nucleoli;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins, Transcription factors
Uniport_ID	Q13129
HGNC ID	HGNC:10025
VEGA ID	OTTHUMG00000005763
OMIM ID	180610
String ID	9606.ENSP00000361857
PharmGKB ID	PA34398

Target gene [RLF] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001619	chr1	10	133	3	146	View
4007993	chr1	13	3	1	17	View
4012665	chr1	2	2		4	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of RLF expression and immune infiltrating cell level correlation result in HIV+ samples
RLF expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of RLF expression and immune infiltrating cell level correlation result in HIV+ samples
RLF expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).