HIV Target gene Detail Information

> RIF1 Gene Search Result


Gene Information
Gene Name RIF1
Gene ID 55183
Gene Full Name replication timing regulatory factor 1
Transcripts ENSG00000080345
Virus HIV
Gene Type protein coding
HPA Location Info Nuclear bodies;Nucleoplasm;Plasma membrane;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q5UIP0
HGNC ID HGNC:23207
VEGA ID OTTHUMG00000131886
OMIM ID 608952
String ID 9606.ENSP00000243326
PharmGKB ID PA134933858
Target gene [RIF1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4001920 chr2 76 25 22 123 View
4006491 chr2 24 24 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of RIF1 expression and immune infiltrating cell level correlation result in HIV+ samples
RIF1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).