HIV Target gene Detail Information

> RIC8A Gene Search Result

Gene Information

Gene Name	RIC8A
Gene ID	60626
Gene Full Name	RIC8 guanine nucleotide exchange factor A
Gene Alias	RIC8
Transcripts	ENSG00000177963
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Plasma membrane;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q9NPQ8
HGNC ID	HGNC:29550
VEGA ID	OTTHUMG00000119069
OMIM ID	609146
String ID	9606.ENSP00000325941
PharmGKB ID	PA142671067

Target gene [RIC8A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4300093	chr11	13	6		19	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of RIC8A expression and immune infiltrating cell level correlation result in HIV+ samples
RIC8A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).