HTLV1 Target gene Detail Information

> RHOU Gene Search Result

Gene Information

Gene Name	RHOU
Gene ID	58480
Gene Full Name	ras homolog family member U
Gene Alias	ARHU; G28K; WRCH1; hG28K; CDC42L1
Transcripts	ENSG00000284984
Virus	HTLV1
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q7L0Q8
HGNC ID	HGNC:17794
VEGA ID	OTTHUMG00000037919
OMIM ID	606366
String ID	9606.ENSP00000355652
PharmGKB ID	PA38246

Target gene [RHOU] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6009543	chr1	18	17	1	36	View
6028535	chr1	1			1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of RHOU expression and immune infiltrating cell level correlation result in HTLV1+ samples
RHOU expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).