HTLV1 Target gene Detail Information

> RHOF Gene Search Result

Gene Information

Gene Name	RHOF
Gene ID	54509
Gene Full Name	ras homolog family member F, filopodia associated
Gene Alias	RIF; ARHF
Transcripts	ENSG00000139725
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Golgi apparatus;Nucleoplasm;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q9HBH0
HGNC ID	HGNC:15703
VEGA ID	OTTHUMG00000169077
OMIM ID	618867
String ID	9606.ENSP00000267205
PharmGKB ID	PA24954

Target gene [RHOF] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6003960	chr12	19	85	30	134	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of RHOF expression and immune infiltrating cell level correlation result in HTLV1+ samples
RHOF expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of RHOF expression and immune infiltrating cell level correlation result in HTLV1+ samples
RHOF expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of RHOF expression and immune infiltrating cell level correlation result in HTLV1+ samples
RHOF expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).