HBV Target gene Detail Information

> RHOB Gene Search Result


Gene Information
Gene Name RHOB
Gene ID 388
Gene Full Name ras homolog family member B
Gene Alias ARH6; ARHB; RHOH6; MST081; MSTP081
Transcripts ENSG00000143878
Virus HBV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Cancer-related genes, Predicted intracellular proteins
Gene Function Suppressor gene
Uniport_ID P62745
HGNC ID HGNC:668
VEGA ID OTTHUMG00000090755
OMIM ID 165370
String ID 9606.ENSP00000272233
Drugbank ID BE0003572
PharmGKB ID PA24950
Target gene [RHOB] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1000210 chr2 581 1616 1877 4074 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of RHOB expression and immune infiltrating cell level correlation result in HBV+ samples
RHOB expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).