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HBV Target gene Detail Information

> RGS7 Gene Search Result


Gene Information
Gene Name RGS7
Gene ID 6000
Gene Full Name regulator of G protein signaling 7
Transcripts ENSG00000182901
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;Mitochondria;
HPA Protein Class Info Plasma proteins, Predicted intracellular proteins
Uniport_ID P49802
HGNC ID HGNC:10003
VEGA ID OTTHUMG00000040107
OMIM ID 602517
String ID 9606.ENSP00000355523
PharmGKB ID PA34378
Target gene [RGS7] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1003836 chr1 21 55 30 106 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of RGS7 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
RGS7 expression: Low -> High
Lollipop of RGS7 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of RGS7 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of RGS7 expression and immune infiltrating cell level correlation result in HBV+ samples
RGS7 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).