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HBV Target gene Detail Information

> RGS3 Gene Search Result


Gene Information
Gene Name RGS3
Gene ID 5998
Gene Full Name regulator of G protein signaling 3
Gene Alias C2PA; RGP3
Transcripts ENSG00000138835
Virus HBV
Gene Type protein coding
HPA Location Info Plasma membrane;
HPA Protein Class Info Plasma proteins, Predicted intracellular proteins
Uniport_ID P49796
HGNC ID HGNC:9999
VEGA ID OTTHUMG00000021048
OMIM ID 602189
String ID 9606.ENSP00000363255
PharmGKB ID PA34374
Target gene [RGS3] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1014363 chr9 1 2 3 View
1400408 chr9 52 23 84 159 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of RGS3 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
RGS3 expression: Low -> High
Lollipop of RGS3 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of RGS3 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of RGS3 expression and immune infiltrating cell level correlation result in HBV+ samples
RGS3 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).