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HBV Target gene Detail Information

> RGS12 Gene Search Result


Gene Information
Gene Name RGS12
Gene ID 6002
Gene Full Name regulator of G protein signaling 12
Transcripts ENSG00000159788
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoli;Nucleoplasm;Cytosol;
HPA Protein Class Info Plasma proteins, Predicted intracellular proteins
Uniport_ID O14924
HGNC ID HGNC:9994
VEGA ID OTTHUMG00000090277
OMIM ID 602512
String ID 9606.ENSP00000339381
PharmGKB ID PA34364
Target gene [RGS12] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1001580 chr4 112 321 171 604 View
1005716 chr4 46 3 49 View
1010878 chr4 7 4 11 View
1012371 chr4 7 7 View
1012657 chr4 6 6 View
1012658 chr4 6 6 View
1017038 chr4 1 1 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of RGS12 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
RGS12 expression: Low -> High
Lollipop of RGS12 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of RGS12 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of RGS12 expression and immune infiltrating cell level correlation result in HBV+ samples
RGS12 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).