HPV Target gene Detail Information

> RGR Gene Search Result

Gene Information

Gene Name	RGR
Gene ID	5995
Gene Full Name	retinal G protein coupled receptor
Gene Alias	RP44
Transcripts	ENSG00000148604
Virus	HPV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins
Gene Function	Oncogene
Uniport_ID	P47804
HGNC ID	HGNC:9990
VEGA ID	OTTHUMG00000018636
OMIM ID	600342
String ID	9606.ENSP00000352427
PharmGKB ID	PA34360

Target gene [RGR] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
5401559	chr10	15			15	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE65858 (GEO)	Head and neck squamous cell carcinoma	270	Head and neck squamous cell carcinoma (EBV+)(73), Head and neck squamous cell carcinoma (EBV-)(197)
HNSC (TCGA)	Head and Neck squamous cell carcinoma	566	Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE65858
HeatMap of cell type fractions in all samples	Lollipop of RGR expression and immune infiltrating cell level correlation result in HPV+ samples
RGR expression: Low -> High

> Dataset: HNSC
HeatMap of cell type fractions in all samples	Lollipop of RGR expression and immune infiltrating cell level correlation result in HPV+ samples
RGR expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).