HIV Target gene Detail Information

> RFX3 Gene Search Result

Gene Information

Gene Name	RFX3
Gene ID	5991
Gene Full Name	regulatory factor X3
Transcripts	ENSG00000080298
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Vesicles;
HPA Protein Class Info	Predicted intracellular proteins, Transcription factors
Uniport_ID	P48380
HGNC ID	HGNC:9984
VEGA ID	OTTHUMG00000019456
OMIM ID	601337
String ID	9606.ENSP00000371434
PharmGKB ID	PA34354

Target gene [RFX3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4005959	chr9	15	9	4	28	View
4007479	chr9	12	7		19	View
4008364	chr9	8	7		15	View
4010774	chr9	8			8	View
4014558	chr9		1	1	2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of RFX3 expression and immune infiltrating cell level correlation result in HIV+ samples
RFX3 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of RFX3 expression and immune infiltrating cell level correlation result in HIV+ samples
RFX3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).