HBV Target gene Detail Information

> RFX2 Gene Search Result


Gene Information
Gene Name RFX2
Gene ID 5990
Gene Full Name regulatory factor X2
Transcripts ENSG00000087903
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;Golgi apparatus;Nucleoplasm;
HPA Protein Class Info Predicted intracellular proteins, Transcription factors
Uniport_ID P48378
HGNC ID HGNC:9983
VEGA ID OTTHUMG00000180711
OMIM ID 142765
String ID 9606.ENSP00000306335
PharmGKB ID PA34353
Target gene [RFX2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1000469 chr19 1133 689 310 2132 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of RFX2 expression and immune infiltrating cell level correlation result in HBV+ samples
RFX2 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).