HBV Target gene Detail Information

> RFX1 Gene Search Result

Gene Information

Gene Name	RFX1
Gene ID	5989
Gene Full Name	regulatory factor X1
Gene Alias	EFC; RFX
Transcripts	ENSG00000288283
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Vesicles;
HPA Protein Class Info	Predicted intracellular proteins, Transcription factors
Uniport_ID	P22670
HGNC ID	HGNC:9982
VEGA ID	OTTHUMG00000181979
OMIM ID	600006
PharmGKB ID	PA34352

Target gene [RFX1] related to virus gene/protein/region

ID	PMID	Mutation	Gene/Protein/Region	Description	Detail
1	21814558	A1762T	BCP	G R C	View
2	21814558	G1613A	C Promoter	G R C	View
3	21814558	G1764A	BCP	G R C	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of RFX1 expression and immune infiltrating cell level correlation result in HBV+ samples
RFX1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).

> Dataset: LIHC