HTLV1 Target gene Detail Information

> REM2 Gene Search Result

Gene Information

Gene Name	REM2
Gene ID	161253
Gene Full Name	RRAD and GEM like GTPase 2
Transcripts	ENSG00000139890
Virus	HTLV1
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q8IYK8
HGNC ID	HGNC:20248
VEGA ID	OTTHUMG00000170277
OMIM ID	616955
String ID	9606.ENSP00000267396
PharmGKB ID	PA134916581

Target gene [REM2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6003899	chr14	131	6		137	View
6019412	chr2	8			8	View
6024625	chr13	2		1	3	View
6025668	chr13	3			3	View
6031142	chr13				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of REM2 expression and immune infiltrating cell level correlation result in HTLV1+ samples
REM2 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of REM2 expression and immune infiltrating cell level correlation result in HTLV1+ samples
REM2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).