HBV Target gene Detail Information

> RELN Gene Search Result

Gene Information

Gene Name	RELN
Gene ID	5649
Gene Full Name	reelin
Gene Alias	RL; ETL7; LIS2; PRO1598
Transcripts	ENSG00000189056
Virus	HBV
Gene Type	protein coding
HPA Location Info	Golgi apparatus;Vesicles;Predicted to be secreted;
HPA Protein Class Info	Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins
Uniport_ID	P78509
HGNC ID	HGNC:9957
VEGA ID	OTTHUMG00000157247
OMIM ID	600514
String ID	9606.ENSP00000392423
PharmGKB ID	PA34323

Target gene [RELN] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1009163	chr7	11	6		17	View
1012593	chr7	6			6	View
1013621	chr7		5		5	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of RELN expression and immune infiltrating cell level correlation result in HBV+ samples
RELN expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).