HBV Target gene Detail Information

> RELB Gene Search Result


Gene Information
Gene Name RELB
Gene ID 5971
Gene Full Name RELB proto-oncogene, NF-kB subunit
Gene Alias IREL; I-REL; IMD53; REL-B
Transcripts ENSG00000104856
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;Cytosol;
HPA Protein Class Info Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors
Uniport_ID Q01201
HGNC ID HGNC:9956
VEGA ID OTTHUMG00000162116
OMIM ID 604758
String ID 9606.ENSP00000221452
PharmGKB ID PA34322
Target gene [RELB] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1003538 chr19 63 51 11 125 View
1015048 chr19 3 3 View
1015049 chr19 3 3 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of RELB expression and immune infiltrating cell level correlation result in HBV+ samples
RELB expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).