HIV Target gene Detail Information

> RDX Gene Search Result

Gene Information

Gene Name	RDX
Gene ID	5962
Gene Full Name	radixin
Gene Alias	DFNB24
Transcripts	ENSG00000137710
Virus	HIV
Gene Type	protein coding
HPA Location Info	Plasma membrane;Nucleoplasm;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Uniport_ID	P35241
HGNC ID	HGNC:9944
VEGA ID	OTTHUMG00000166574
OMIM ID	179410
String ID	9606.ENSP00000384136
Drugbank ID	BE0004516
PharmGKB ID	PA34311

Target gene [RDX] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4004318	chr11	45	1		46	View
4005813	chr11	28	1		29	View
4006627	chr11	23			23	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of RDX expression and immune infiltrating cell level correlation result in HIV+ samples
RDX expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of RDX expression and immune infiltrating cell level correlation result in HIV+ samples
RDX expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).