HTLV1 Target gene Detail Information

> RDH10 Gene Search Result

Gene Information

Gene Name	RDH10
Gene ID	157506
Gene Full Name	retinol dehydrogenase 10
Gene Alias	SDR16C4
Transcripts	ENSG00000121039
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Lipid droplets;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Enzymes, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q8IZV5
HGNC ID	HGNC:19975
VEGA ID	OTTHUMG00000164492
OMIM ID	607599
String ID	9606.ENSP00000240285
PharmGKB ID	PA134989620

Target gene [RDH10] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6008410	chr8	30	4	11	45	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of RDH10 expression and immune infiltrating cell level correlation result in HTLV1+ samples
RDH10 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of RDH10 expression and immune infiltrating cell level correlation result in HTLV1+ samples
RDH10 expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of RDH10 expression and immune infiltrating cell level correlation result in HTLV1+ samples
RDH10 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).