HIV Target gene Detail Information

> RCOR3 Gene Search Result

Gene Information

Gene Name	RCOR3
Gene ID	55758
Gene Full Name	REST corepressor 3
Transcripts	ENSG00000117625
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Cytosol;
HPA Protein Class Info	Predicted intracellular proteins, Transcription factors
Uniport_ID	Q9P2K3
HGNC ID	HGNC:25594
VEGA ID	OTTHUMG00000036996
String ID	9606.ENSP00000413929
PharmGKB ID	PA134917623

Target gene [RCOR3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4004712	chr1	22	5	13	40	View
4005195	chr1	26	9		35	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of RCOR3 expression and immune infiltrating cell level correlation result in HIV+ samples
RCOR3 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of RCOR3 expression and immune infiltrating cell level correlation result in HIV+ samples
RCOR3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).