HIV Target gene Detail Information

> RCAN3 Gene Search Result

Gene Information

Gene Name	RCAN3
Gene ID	11123
Gene Full Name	RCAN family member 3
Gene Alias	RCN3; MCIP3; hRCN3; DSCR1L2
Transcripts	ENSG00000117602
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nuclear speckles;Nucleoli fibrillar center;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q9UKA8
HGNC ID	HGNC:3042
VEGA ID	OTTHUMG00000003298
OMIM ID	605860
String ID	9606.ENSP00000363516
PharmGKB ID	PA162400972

Target gene [RCAN3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4006035	chr1	22	5		27	View
4007421	chr1	3	5	11	19	View
4011025	chr1	5	2		7	View
4011666	chr1	2	4		6	View
4014110	chr1	1	1		2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of RCAN3 expression and immune infiltrating cell level correlation result in HIV+ samples
RCAN3 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of RCAN3 expression and immune infiltrating cell level correlation result in HIV+ samples
RCAN3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).