HTLV1 Target gene Detail Information

> RCAN1 Gene Search Result

Gene Information

Gene Name	RCAN1
Gene ID	1827
Gene Full Name	regulator of calcineurin 1
Gene Alias	CSP1; DSC1; RCN1; DSCR1; MCIP1; ADAPT78
Transcripts	ENSG00000159200
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Cytosol;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	P53805
HGNC ID	HGNC:3040
VEGA ID	OTTHUMG00000086235
OMIM ID	602917
String ID	9606.ENSP00000370527
Drugbank ID	BE0008933
PharmGKB ID	PA162400946

Target gene [RCAN1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6003173	chr21	135	26	16	177	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of RCAN1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
RCAN1 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of RCAN1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
RCAN1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).