HIV Target gene Detail Information

> RBPJ Gene Search Result

Gene Information

Gene Name	RBPJ
Gene ID	3516
Gene Full Name	recombination signal binding protein for immunoglobulin kappa J region
Gene Alias	SUH; csl; AOS3; CBF1; KBF2; RBP-J; RBPJK; IGKJRB; RBPSUH; IGKJRB1
Transcripts	ENSG00000168214
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins, Transcription factors
Uniport_ID	Q06330
HGNC ID	HGNC:5724
VEGA ID	OTTHUMG00000097793
OMIM ID	147183
String ID	9606.ENSP00000345206
PharmGKB ID	PA34292

Target gene [RBPJ] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001240	chr4	81	9	99	189	View
4007863	chr4	17			17	View
4010327	chr4	8	1		9	View
4012160	chr4	5			5	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of RBPJ expression and immune infiltrating cell level correlation result in HIV+ samples
RBPJ expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of RBPJ expression and immune infiltrating cell level correlation result in HIV+ samples
RBPJ expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).