HIV Target gene Detail Information

> RBM5 Gene Search Result

Gene Information

Gene Name	RBM5
Gene ID	10181
Gene Full Name	RNA binding motif protein 5
Gene Alias	G15; H37; RMB5; LUCA15; LUCA-15
Transcripts	ENSG00000003756
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins
Gene Function	Suppressor gene
Uniport_ID	P52756
HGNC ID	HGNC:9902
VEGA ID	OTTHUMG00000156785
OMIM ID	606884
String ID	9606.ENSP00000343054
PharmGKB ID	PA34267

Target gene [RBM5] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001712	chr3	134	3		137	View
4005017	chr3	30	7		37	View
4013372	chr3	3			3	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of RBM5 expression and immune infiltrating cell level correlation result in HIV+ samples
RBM5 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of RBM5 expression and immune infiltrating cell level correlation result in HIV+ samples
RBM5 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).