HIV Target gene Detail Information

> RBM45 Gene Search Result


Gene Information
Gene Name RBM45
Gene ID 129831
Gene Full Name RNA binding motif protein 45
Gene Alias DRB1; RB-1
Transcripts ENSG00000155636
Virus HIV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Plasma proteins, Predicted intracellular proteins
Uniport_ID Q8IUH3
HGNC ID HGNC:24468
VEGA ID OTTHUMG00000154202
OMIM ID 608888
String ID 9606.ENSP00000286070
PharmGKB ID PA162400809
Target gene [RBM45] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4005487 chr2 31 1 32 View
4008959 chr2 8 5 13 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of RBM45 expression and immune infiltrating cell level correlation result in HIV+ samples
RBM45 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of RBM45 expression and immune infiltrating cell level correlation result in HIV+ samples
RBM45 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).