HIV Target gene Detail Information

> RBM4 Gene Search Result

Gene Information

Gene Name	RBM4
Gene ID	5936
Gene Full Name	RNA binding motif protein 4
Gene Alias	LARK; RBM4A; ZCRB3A; ZCCHC21
Transcripts	ENSG00000173933
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Cytosol;
HPA Protein Class Info	Predicted intracellular proteins
Gene Function	Suppressor gene
Uniport_ID	Q9BWF3
HGNC ID	HGNC:9901
VEGA ID	OTTHUMG00000154171
OMIM ID	602571
String ID	9606.ENSP00000386894
PharmGKB ID	PA34266

Target gene [RBM4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003549	chr11	48	11		59	View
4003675	chr11	56			56	View
4004388	chr11	44	1		45	View
4004490	chr11	42	1		43	View
4005625	chr11	22	9		31	View
4010669	chr11	6		2	8	View
4010670	chr11	8			8	View
4011823	chr11	6			6	View
4011871	chr11	1	3	2	6	View
4013079	chr11	1	3		4	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of RBM4 expression and immune infiltrating cell level correlation result in HIV+ samples
RBM4 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of RBM4 expression and immune infiltrating cell level correlation result in HIV+ samples
RBM4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).