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HTLV1 Target gene Detail Information

> RBM19 Gene Search Result


Gene Information
Gene Name RBM19
Gene ID 9904
Gene Full Name RNA binding motif protein 19
Gene Alias Mrd1
Transcripts ENSG00000122965
Virus HTLV1
Gene Type protein coding
HPA Location Info Nucleoli;
HPA Protein Class Info Plasma proteins, Predicted intracellular proteins
Uniport_ID Q9Y4C8
HGNC ID HGNC:29098
VEGA ID OTTHUMG00000169646
OMIM ID 616444
String ID 9606.ENSP00000442053
PharmGKB ID PA134886784
Target gene [RBM19] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6011027 chr12 10 13 5 28 View
6017190 chr12 11 11 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of RBM19 expression and immune infiltrating cell level correlation result in HTLV1+ samples
RBM19 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of RBM19 expression and immune infiltrating cell level correlation result in HTLV1+ samples
RBM19 expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of RBM19 expression and immune infiltrating cell level correlation result in HTLV1+ samples
RBM19 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).