HIV Target gene Detail Information

> RBM15 Gene Search Result

Gene Information

Gene Name	RBM15
Gene ID	64783
Gene Full Name	RNA binding motif protein 15
Gene Alias	OTT; OTT1; SPEN
Transcripts	ENSG00000162775
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins
Gene Function	Oncogene
Uniport_ID	Q96T37
HGNC ID	HGNC:14959
VEGA ID	OTTHUMG00000011284
OMIM ID	606077
String ID	9606.ENSP00000358799
PharmGKB ID	PA34264

Target gene [RBM15] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4004486	chr1	12	3	28	43	View
4006354	chr1	2	8	15	25	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of RBM15 expression and immune infiltrating cell level correlation result in HIV+ samples
RBM15 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of RBM15 expression and immune infiltrating cell level correlation result in HIV+ samples
RBM15 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).